Recently, various physics-based approaches have been proposed to compute intrinsic aqueous solubility, specifically the equilibrium solubility of the neutral form of the solute, written as S. 0.

Price was educated at the University of Cambridge, where she was awarded a Bachelor of Arts degree in 1977 followed by a PhD in 1980. [6][8] Her doctoral research modelled the intermolecular forces …

Sally Price’s group is concerned with modelling the intermolecular and intramolecular forces in organic molecules, such as pharmaceuticals, sufficiently realistically that they can be used for predicting the …

May 1, 2022 · Here, we elucidate these standardized solubility practices for drug candidates in early drug development and probe their integration into drug discovery solubility-screening assays.

We demonstrate that physics-based calculations of intrinsic aqueous solubility can rival cheminformatics-based machine learning predictions.

Sally, officially Sarah, Price trained as a theoretical chemist at the University of Cambridge, specialising in deriving models of the forces between molecules from their wavefunctions.

”Why don’t we find more polymorphs?” by SL Price, 2013, Acta Crystallography, B69, 313-328. Invited Lead Article, reproduced in special collection publicizing the journal, discussing the interplay between …

Read articles by Sarah L. Price on ScienceDirect, the world's leading source for scientific, technical, and medical research.

Professor S. L. Price MA PhD CCHEM FRSC Professor of Chemistry On Editorial Board of RSC Electronic Journal CrystEngComm Topic Editor for ACS Journal Crystal Growth & Design

Thus, the group are interested in predicting the properties of organic crystals, such as solubility, morphology, elastic tensor, diamagnetic susceptibity, phonon, solid-state NMR and diffraction …