The class of drugs known as DNA Damage Response inhibitors, which work by blocking cancer cells’ ability to repair their own damaged DNA, is expanding rapidly beyond its original anchor, the PARP ...

Pancreatic cancer is one of the deadliest cancers and the third-leading cause of cancer-related death in the United States.

Researchers from the MRC Protein Phosphorylation and Ubiquitylation Unit at the University of Dundee, together with collaborators from ETH Zürich, the Malopolska Center of Biotechnology and the ...

Cancer cells often survive treatment by fixing the DNA damage that therapy is meant to cause. Researchers found that UNI418 ...

Hyperreactivity of the gene responsible for DNA repair may indicate a hidden vulnerability of oncological diseases and help ...

Add Yahoo as a preferred source to see more of our stories on Google. Double-strand breaks in DNA can be deadly. Victor Golmer/iStock via Getty Images Plus Your DNA is continually damaged by sources ...

The human genome consists of 3 billion base pairs, and when a cell divides, it takes about seven hours to complete making a copy of its DNA. That's almost 120,000 base pairs per second. At that ...

Newborn nerve cells must squeeze through crowded, narrow spaces—through dense tissue, past other cells, and between fibers—to ...

As newborn neurons make their way through the developing brain, they must squeeze through incredibly tight spaces to reach their final destinations. Researchers discovered that this physical journey ...

Following a double-strand DNA break, an enzyme called PARP1 helps hold the two strands together —like superglue— and creates a safe zone for other proteins to come repair the damage. We don’t exactly ...

Scientists discovered a protein that helps plants repair DNA damage from sunlight, which could improve future crop gene ...