Dissecting complex genetic and epigenetic alterations in cancer genomes using CpG island microarrays
We describe a high-throughput approach for investigating both copy number alterations and aberrant methylation of CpG islands in human cancer. The technique involves generation of a microarray panel ...
Comparative genomic hybridization (CGH) was developed to identify pathogenic DNA copy-number changes (e.g., duplications, deletions) on a genome-wide scale, and to map these changes to genomic ...
Development of an immunoglobin variable region specific DNA microarray: Analysis of B-Cell clonality
The prophylactic use of lamivudine can maintain dose-intensity of doxorubicin in hepatitis-B surface antigen (HBs Ag)-positive patients with non-Hodgkin's lymphoma who received cytotoxic chemotherapy ...
Chongwei Shi Advances Genetic Research Through DNA Microarray Technology Principles and Applications
A recent study highlights how DNA microarray technology enables high-throughput gene analysis, supporting variation detection, expression profiling, and clinical research. By refining probe design and ...
The Geniom® RT Analyzer, a new benchtop microarray processing instrument, was presented by febit at Select Bioscience’s “Advances in Microarray Technology”. The platform complements Geniom® One, the ...
In this issue we take a close look at DNA microarrays, the current amore of biological and biomedical researchers. There's little reason to doubt that the infatuation will continue, at least for ...
In the early 1980s, David Gilmour, now an emeritus biochemistry and molecular biology professor at Pennsylvania State University, joined the laboratory of geneticist and biochemist John Lis as a ...
Launched in 1990, The Human Genome Project was a monumental effort to sequence and analyze the entire human genome to understand how genetics influence health. While the Human Genome Project helped ...
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